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Researchers set out to compare the impact of whey versus collagen protein on muscle loss during periods of inactivity and then recoveryin resistance-trained males. In a separate study on 18 male resistance-trained individuals, they found that, whereas collagen protein caused a significant decline in body weight and fat area, whey protein produced a significant improvement in muscular strength and performance. Both protein sources also increased lean mass to an astonishing extent. These two studies were the first of their kind to directly establish that protein supplements might aid in weight loss and muscle mass reduction in a scientifically validated study design. In the first study, they found the whey-derived protein had a dose-dependent effect on muscle metabolism and, importantly, that it had a greater effect on the amount of protein that remained in the bloodstream for longer than did the collagen-derived protein. They also tested the protein in the absence of carbohydrate. The researchers found that their sample of 18 young, lean individuals who were performing resistance-training with resistance-training implements exhibited a higher peak energy expenditure and an attenuated energy expenditure associated with an increase in total daily protein intake (from 0.3 to 0.4 grams per kilogram of bodyweight). In the second study, they tested the effect of whey versus collagen protein on a whole range of performance factors in resistance-trained males. Specifically, they tested the impact of whey protein on maximal power (Pmax), and at rest and during exercise. They found a significant difference (P < 0.005) that whey-based protein had a greater impact (P < 0.005) in Pmax, while that collagen-based protein had a more beneficial effect in strength and power. The researchers argue that whey protein has an advantage in reducing body weight through a direct protein delivery mechanism, whereas its ability to promote muscle protein synthesis, a major contributor to lean mass, allows it to more effectively contribute to lean mass recovery. They also believe that there are benefits to a high-fat meal, such as increasing satiety and reducing satiety hormones, that they do not see with whey protein supplements. In a review publication of their research conducted by the same authors, researchers concluded: "The research evidence points towards potential application of whey protein in individuals with specific food restrictions, and it is unclear whether this is optimal or if whey protein can replace protein intakes of low quality in people with these nutritional requirements." They also suggest the studies of Dr. Thomas were a useful starting point for conducting better studies of the effects of protein supplements. Whey's Impact on Muscle Loss in Related Article: